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The most effective GLP-1 drug for weight loss currently (as of mid-2025) is tirzepatide, marketed under the names Zepbound (for weight loss) and Mounjaro (for diabetes). Clinical trials and recent meta-analyses consistently show tirzepatide delivers the most substantial weight reduction among GLP-1 medications, with average losses of up to 22.5 of body weight, outperforming semaglutide ... This aspect of Collins Dictionary Word Of The Day plays a vital role in practical applications.
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