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Furthermore, the hypothalamic-pituitary-adrenal axis (HPA) is the main stress response system. It is the neuroendocrine link between perceived stress and physiological reactions to stress (Breedlove and Watson, 2013). The primary function of the activated HPA axis is to release glucocorticoids that activate short-term physiological responses to stress. This aspect of Hypothalamicpituitaryadrenal Axis Wikipedia plays a vital role in practical applications.

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